The hospital said there is “no indication” that Slayman’s death “was the result of his recent transplant.”

As animal-to-human transplants are crucial to ease the huge organ shortage, Slayman's case has been hailed as a historic milestone. As human immune system destroys foreign animal tissue, a genetically modified pig kidney was transplanted on Slayman.

BOSTON, May 14: Richard Slayman, the first patient to receive a genetically modified pig kidney, has died two months after the xenotransplantation at Massachusetts General Hospital in Boston, it was announced last Saturday.

The four-hour surgery performed on March 16 marked a major milestone in the quest to provide more readily available organs to patients, the hospital had said.

As animal-to-human transplants are crucial to ease the huge organ shortage, Slayman's case has been hailed as a historic milestone. As human immune system destroys foreign animal tissue, a genetically modified pig kidney was transplanted on Slayman.

The hospital said there is “no indication” that Slayman’s death “was the result of his recent transplant.”

There have also been transplants of other pig organs. Maryland surgeons transplanted a pig heart on a dying patient but he survived only two months.

Much before Slayman's case, a genetically modified pig kidney was transplanted on one Maurice Miller, 57, who had cancer and was brain dead, at NYU Langone in New York City. He died on September 12, 2023, after 61 days. The pig kidney worked normally inside his brain-dead body. Alongwith the modified pig kidney, the thymus was also transplanted, . beneath the kidney. That was to prevent the transplanted kidney from being attacked by the human immune system by learning to recognize the pig antigens as its own.

In another case, the University of Alabama at Birmingham found two gene-edited pig kidneys functioned for seven days in a brain-dead recipient. It also used "immunosuppression drugs."

Slayman, 62, a resident of Weymouth, near Boston. had been living with Type 2 diabetes and hypertension for many years. He was on dialysis for many years before receiving a kidney transplant from a human deceased donor in December 2018 at Massachusetts General Hospital. It worked for five years and he was back to dialysis in May 2023.

He underwent the pig kidney transplantation surgery on March 16. It took six hours. The pig's kidney had received 69 edits to prevent rejection by the patient's immune system. He was quite happy when he left the hospital on April 2 that he was no more required to undergo dialysis - “free from the burden of dialysis that has affected my quality of life for many years.”

The pig kidney was provided by eGenesis, a pharmaceutical company, from a pig donor genetically-edited using CRISPR-Cas9 technology. Certain pig genes were removed and some human genes were added.

The hospital said that Slayman “will forever be seen as a beacon of hope to countless transplant patients worldwide.”

There are over a lakh patients waiting for kidney transplant in the US.

One of them is seen in CCTV being shot at close range. The motive is suspected to be personal enmity.

TAILPIECE: Almost every other day we hear of shootings in one place or other in the country. India will very soon replace the US as the world's No 1 in the incidence of mass shooting. It will eclipse terrorism as a source of concern. Who can help? At least, has it occurred to anyone's mind?

'This Moment' of Shakti fusion won the Best Global Music Album at the Grammys. Zakir Hussain has won two other awards too. In a great victory for Indians, five of them have won the Grammys this time. In other sections, Taylor Swift got her fourth Album of the Year award and Miley Cyrus got an award for the first time.

The Government scheme provides ₹ 51,000 per wedding of which ₹ 35,000 goes to the girl, ₹ 10,000 for wedding materials and ₹ 6,000 towards expenses for the ceremony.

“Two activists from the environmental movement ‘Riposte Alimentaire’ sprayed pumpkin soup on the armoured glass protecting the Mona Lisa, this Sunday, January 28, 2024, around 10 am (4aET),” a statement from the museum said.

It is not understood how undesirable elements are allowed to get so close to her and play havoc with the artwork. Several times over this has happened in the past, deranged minds masquerading as tourists and cultists venting their frustration.

A Spicejet passenger had a harrowing experience inside a tiny claustrophobic lavatory aboard a Mumbai-Bengaluru flight when he found to his bewilderment that the door was not opening.

Two days earlier, in a similar incident in the area, a domestic help was bitten by a pet dog in the lift when she was going for work.

Tailpiece: Sometimes appearing to outnumnber men and women on the streets, the stray dogs are turning more and more daring with sections of anti-social elements out there to feed and protect them in order to find a window for their unfulfilled love! There is an all-pervading feeling of lack of authority.

Ankit Tiwari had told the employee that “instructions had been received from the Prime Minister’s Office to conduct an enquiry” and reopen the “already disposed of” case and asked him to appear before the ED office at Madurai on October 30, DVAC said. The doctor was allegedly threatened with arrest and told to pay a bribe of Rs 3 cr to avoid the ED probe, which was later negotiated down to Rs 50 lakh.

Tailpiece: We are made to believe RBI, CBI, ED, Judiciary as sacrosanct and all others like railways, transport, revenue, education, PWD departments are composed of us the mortals, absolutely corrupt! As if in the sacrosanct places the angels descend from the heavens to work in the night and fly away before day-break! Let's be true to ourselves, we are all cut from the same cloth.

Apart from cash, Gill had also taken three planes as bribe and two of them were leased out to Redbird Aviation Academy. With the result, flying schools compromised on safety requirements and trainers met with accidents several times.

Five people were arrested from a banquet hall in Sector 51 Noida on Thursday where they were called to hold a rave party in a trap laid by the animal rights group, PFA. They named Yadav but he was not present.

Betting through Dubai-based Mahadev Book in India is conducted through a countrywide network. Probes reveal that the online gambling is worth several millions and top politicians, officials and celebs have been beneficiaries.

TAILPIECE: Polling dates for some States are round the corner. Top politicians have begun their acrimonious debate who looted more, even as Mahadev is washing their dirty laundry in the open ghat. Come what may, one needs to seize power to amass "thy wretched pelf!" One simple question is, why else one should spend lakhs or crores to get elected! A question every Indian should ask to oneself at least once a day!

His inaction amounts to defeating the rights of the people of the State to welfare measures sought to be implemented through the Bills, the Kerala Government's petition submitted, while the State of Tamil Nadu remarked that its "Governor is acting as a political rival."

Tailpiece: Coming up back to back, the petitions in their totality seem to question the provision of Raj Bhavan, and not motives of a Governor as a person.

Hundreds of cars piled up behind the wreckage of crashes occurring one after other in backing up - continuous crashes to the rhythm of metallic clanks and bangs back to back. According to reports, some ops required 'Jaws of Life' to pull apart the mangled cars to save lives inside.

The pilots struggled with Emerson to thwart a shut-off as he reached for the T-handles (see pix). Later he admitted to police he had taken psychedelic mushrooms and had a "nervous breakdown."

Doctors reasoned how the incidence of heart attacks is spiking over time and advise the simple way to play safely is to take a break and rehydrate yourself.

But how come ten people, including children, die of cardiac arrest at Garba in 24 hours, and that at different places of Gujarat? Garba had been going on for six days, and every year it is celebrated.

The killing of a teacher in France by an Islamic radical last Friday is linked to the Israel-Hamas war in West Asia, say authorities.

Shocking news from the UK: Leading grocers have started bribing policemen with free food and drinks to persuade them to take action against shoplifters.

Shoplifting has risen by about 27 per cent in 10 major cities across the UK this year. The cost of retail crime last year was $2.15 billion. Besides, “We are seeing organised gangs threatening staff with weapons and emptying stores," Helen Dickinson, chief executive of the British Retail Consortium, said. Data shows that the police failed to respond to 73 per cent of serious retail crimes that included assault and abuse of workers, apart from shoplifting.

Isar Mohammad allegedly picked up a banana offered to Ganesh idol on Chaturthi at a makeshift temple in Delhi and consumed it.

Harris said hip-hop is “the ultimate American art form” that “shapes every aspect of American popular culture.” “Hip-hop culture is American culture,” she said in a talk at her official residence at the US Naval Observatory in Washington, D.C.

The social media had mixed reaction. There was much appreciation that she dances better than any VP in American history. But some called her "moves" as “cringe” while others did not like her pink pants - "pink pants don’t look good.” In fact, her ensembles have always been incongruous.

"Let’s see how the (Governor's) Vice-Chancellors are given salary." Mamata's extreme statements will put the Marxist Government in Kerala, which is also facing similar issues, to shame. Has she begun the countdown for a war on the streets?

It's true Mamata has come to see a conspiracy to demolish the established systems across the country, but lacks the ability to foresee what exactly is being pushed.